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Feasibility and effectiveness of electrochemical dermal conductance measurement for the screening of diabetic neuropathy in primary care. DECODING Study (Dermal Electrochemical Conductance in Diabetic Neuropathy). Rationale and design

Publicated to:Medicine. 97 (20): e10750-e10750 - 2018-05-01 97(20), DOI: 10.1097/MD.0000000000010750

Authors: Cabre, Juan J; Mur, Teresa; Costa, Bernardo; Barrio, Francisco; Lopez-Moya, Charo; Sagarra, Ramon; Garcia-Barco, Montserrat; Vizcaino, Jesus; Bonaventura, Immaculada; Ortiz, Nicolau; Flores-Mateo, Gemma

Affiliations

- Author
Catalan Hlth Inst, Jordi Gol Primary Care Res Inst, Primary Hlth Care Div, Reus, Catalonia, Spain - Author
Hosp Univ Mutua Terrassa, Dept Neurol, Barcelona, Spain - Author
Hosp Univ St Joan de Reus, Dept Neurol, Tarragona, Spain - Author
Jordi Gol Primary Care Research Institute, Catalan Health Institute, Primary Health Care Division, Reus-Barcelona, Catalonia Mútua Terrassa Primary Care, Terrassa, Barcelona Department of Neurology, Hospital Universitari Mútua Terrassa, Terrassa, Barcelon - Author
Mutua Terrassa Primary Care, Barcelona, Spain - Author
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Abstract

Diabetes mellitus is the leading cause of polyneuropathy in the Western world. Diabetic neuropathy is a frequent complication of diabetes and may have great clinical transcendence due to pain and possible ulceration of the lower extremities. It is also a relevant cause of morbidity and mortality in patients with diabetes. Although the cause of polyneuropathy in patients with diabetes is only partially known, it has been associated with chronic hyperglycemia suggesting the possible etiopathogenic implication of advanced glycosylation end products. The strategy of choice in the medical management of diabetic neuropathy is early detection since glycaemic control and the use of certain drugs may prevent or slow the development of this disease. Diabetic neuropathy most often presents with a dysfunction of unmyelinated C-fibers, manifested as an alteration of the sweat reflex of the eccrine glands. This dysfunction can now be demonstrated using a newly developed technology which measures dermal electrochemical conductivity. This noninvasive test is easy and cost-effective. The aim of the present study is to evaluate the feasibility and effectiveness of dermal electrochemical conductance measurement (quantitative expression of the sudomotor reflex) as a screening test for the diagnosis of diabetic neuropathy in patients in primary care.

Keywords
AdultDermal electrochemical conductanceDiabetes mellitusDiabetes mellitus, type 2Diabetic neuropathiesDimensional measurement accuracyElectrochemical techniquesFeasibility studiesFemaleGalvanic skin responseHumansMaleMass screeningMiddle agedNeuropathyPrimary carePrimary health careReproducibility of resultsScreeningSpainSudomotor reflex

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Medicine due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2018, it was in position 69/160, thus managing to position itself as a Q2 (Segundo Cuartil), in the category Medicine, General & Internal. Notably, the journal is positioned en el Cuartil Q2 para la agencia Scopus (SJR) en la categoría Medicine (Miscellaneous).

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2025-05-11:

  • Google Scholar: 2
  • WoS: 2
  • Scopus: 2
  • Europe PMC: 1
  • OpenCitations: 2
Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-11:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 62.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 62 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 0.25.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: http://hdl.handle.net/20.500.11797/imarina5132955