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We want to acknowledge particularly the participants and the IGTP-HUGTP (B.0000643) and IRBLleida (B.0000682) Biobanks integrated into the PLATAFORMA BIOBANCOS (PT20/00050 and PT20/00021, respectively).

Analysis of institutional authors

Alonso, NuriaAuthor

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Article

Choroidal thickness as predictor of subclinical carotid atherosclerosis in adults with type 1 diabetes

Publicated to:Scientific Reports. 15 (1): 8360- - 2025-03-11 15(1), DOI: 10.1038/s41598-025-93534-z

Authors: Castelblanco, Esmeralda; Salvador-Miras, Ignacio; Carbonell, Marc; Gratacos, Monica; Traveset, Alicia; Correig, Eudald; Hernandez, Marta; Alonso, Nuria; Franch-Nadal, Josep; Mauricio, Didac

Affiliations

Arnau de Vilanova Univ Hosp, Dept Ophthalmol, Lleida 25198, Spain - Author
Autonomous Univ Barcelona, Dept Med, Barcelona 08193, Spain - Author
Fundacio Inst Univ Recerca Atencio Primaria Salut, DAP Cat Grp, Unitat Suport Recerca Barcelona, Barcelona 08007, Spain - Author
Germans Trias & Pujol Univ Hosp, Dept Endocrinol & Nutr, Badalona 08916, Spain - Author
Germans Trias & Pujol Univ Hosp, Dept Pathol, Badalona 08916, Spain - Author
Hosp Arnau Vilanova, Dept Endocrinol & Nutr, Lleida 25198, Spain - Author
Hosp Santa Creu & Sant Pau, Dept Endocrinol & Nutr, St Quinti 89, Barcelona 08041, Spain - Author
Inst Invest Biomed St Pau IIB St Pau, Barcelona 08041, Spain - Author
Inst Salud Carlos III, CIBER Diabet & Enfermedades Metab Asociadas, Madrid 28029, Spain - Author
Lleida Biomed Res Inst IRBLleida, Lleida 25198, Spain - Author
Univ Rovira & Virgili, Dept Biostat, Reus 43201, Spain - Author
Univ Vic UVIC UCC, Fac Med, Vic 08500, Spain - Author
Washington Univ, Sch Med, Dept Med, Div Endocrinol Metab & Lipid Res, St Louis, MO 63110 USA - Author
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Abstract

Patients with Type 1 Diabetes (T1DM) have a higher risk of cardiovascular disease. This study used carotid ultrasound to identify subclinical carotid plaques and Optical Coherence Tomography (OCT) to evaluate ophthalmological markers as predictors of carotid plaque presence in 242 adults with T1DM, employing machine learning models for early risk assessment. Individuals with carotid plaques (N = 67) did not show significant differences in retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) and inner plexiform layer (IPL) complex compared to those without (N = 175). However, subfoveal and temporal choroidal area thickness significantly decreased in individuals with plaques (P

Keywords

AdultCardiovascular riskCarotid artery diseasesCarotid artery plaqueChildrenChoroidChoroid thicknessCoronaryDiabetes mellitus, type 1DiseaseFemaleGanglion-cell layerHumansIntima-media thicknessLong-termMachine learninMachine learningMaleMellitusMiddle agedNerve-fiber layerOptical coherence tomographyPlaquPlaque, atheroscleroticRisk factorsSubclinical atherosclerosisTomography, optical coherenceType 1 diabetes mellitus

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Scientific Reports due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2025, it was in position 25/134, thus managing to position itself as a Q1 (Primer Cuartil), in the category Multidisciplinary Sciences.

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-06-27:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 1 (PlumX).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: United States of America.