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Richart Jurado, Cristobal ManuelAuthorSalas-Salvado, JAuthor or co-author of article in journal with external admissions assessment committee

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May 13, 2014
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White fish reduces cardiovascular risk factors in patients with metabolic syndrome: The WISH-CARE study, a multicenter randomized clinical trial

Publicated to:Nutrition Metabolism And Cardiovascular Diseases. 24 (3): 328-335 - 2014-03-01 24(3), DOI: 10.1016/j.numecd.2013.09.018

Authors: Vazquez, C; Botella-Carretero, J I; Corella, D; Fiol, M; Lage, M; Lurbe, E; Richart, C; Fernandez-Real, J M; Fuentes, F; Ordonez, A; de Cos, A I; Salas-Salvado, J; Burguera, B; Estruch, R; Ros, E; Pastor, O; Casanueva, F F

Affiliations

Hosp Clin Barcelona, Dept Internal Med, Barcelona, Spain - Author
Hosp Clin Barcelona, IDIBAPS Hipertens Lipidos & Riesgo Cardiovasc, Unit Lipids, Barcelona, Spain - Author
Hosp Gen Valencia, Valencia, Spain - Author
Hosp Josep Trueta, Dept Endocrinol, Girona, Spain - Author
Hosp Univ La Paz, Dept Obes, Madrid, Spain - Author
Hosp Univ Ramon y Cajal, Dept Biochem, IRYCIS, Madrid 28034, Spain - Author
Hosp Univ Ramon y Cajal, Inst Ramon y Cajal Invest Sanitaria IRYCIS, Dept Clin Nutr & Obes, Madrid 28034, Spain - Author
Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBERObn, Madrid, Spain - Author
Univ Barcelona, Dept Med, Barcelona, Spain - Author
Univ Barcelona, Hosp Clin Barcelona, Dept Med, Barcelona, Spain - Author
Univ Cordoba, IMIBIC Hosp Univ Reina Sofia, Unidad Lipidos & Arteriosclerosis, E-14071 Cordoba, Spain - Author
Univ Illes Balears, Hosp Son Dureta, Div Endocrinol, Palma De Mallorca, Spain - Author
Univ Illes Balears, Hosp Univ Son Espases, Inst Univ Invest Ciencias Salud, Dept Surg Cardiol, Palma De Mallorca, Spain - Author
Univ Rovira & Virgili, Hosp Univ Juan 23, Dept Med, E-43007 Tarragona, Spain - Author
Univ Rovira & Virgili, Hosp Univ St Joan de Reus, IISPV, Human Nutr Unit, E-43201 Reus, Spain - Author
Univ Santiago de Compostela, Div Endocrinol, Santiago De Compostela, Spain - Author
Univ Valencia, Sch Med, Dept Prevent Med, Valencia, Spain - Author
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Abstract

Reduction of cardiovascular risk with high consumption of fish in diet is still a matter of debate, and concerns about heavy metal contamination have limited consumption of oily fish. We aimed to evaluate the effect of regular ingestion of white fish on cardiovascular risk factors in patients with metabolic syndrome.Multicenter randomized crossover clinical trial including 273 individuals with metabolic syndrome. An 8-week only-one dietary intervention: 100 g/d of white fish (Namibia hake) with advice on a healthy diet, compared with no fish or seafood with advice on a healthy diet. Outcomes were lipid profile, individual components of the metabolic syndrome, serum insulin concentrations, homeostasis model of insulin resistance, serum C-reactive protein and serum fatty acid levels. We found a significant lowering effect of the intervention with white fish on waist circumference (P < 0.001) and diastolic blood pressure (P = 0.014). A significant lowering effect was also shown after the dietary intervention with fish on serum LDL concentrations (P = 0.048), whereas no significant effects were found on serum HDL or triglyceride concentrations. A significant rise (P < 0.001) in serum EPA and DHA fatty acids was observed following white fish consumption. Overall adherence to the intervention was good and no adverse events were found.In individuals with metabolic syndrome, regular consumption of hake reduces LDL cholesterol concentrations, waist circumference and blood pressure components of the metabolic syndrome.White Fish for Cardiovascular Risk Factors in Patients with Metabolic Syndrome Study, Registered under ClinicalTrials.gov Identifier: NCT01758601.Copyright © 2013 Elsevier B.V. All rights reserved.

Keywords

blood pressurecardiovascular riskldl cholesterolmetabolic syndromewaist circumferenceBlood pressureCardiovascular riskLdl cholesterolMetabolic syndromeWaist circumferenceWhite fish

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Nutrition Metabolism And Cardiovascular Diseases due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2014, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Medicine (Miscellaneous). Notably, the journal is positioned above the 90th percentile.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.21. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 1.43 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 7.69 (source consulted: Dimensions Jul 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-07-25, the following number of citations:

  • WoS: 44
  • Scopus: 46
  • Europe PMC: 25
  • Google Scholar: 56

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-25:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 151.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 157 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 5.5.
  • The number of mentions on the social network Facebook: 1 (Altmetric).
  • The number of mentions on the social network X (formerly Twitter): 3 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is: