{rfName}
Ch

Indexed in

License and use

Citations

21

Altmetrics

Analysis of institutional authors

Cataffo AAuthorEchavarren AmAuthor

Share

Publications
>
Article

Chiral Auxiliary Approach for Gold(I)-Catalyzed Cyclizations

Publicated to:Angewandte Chemie (International Ed. Print). 62 (49): e202312874- - 2023-11-06 62(49), DOI: 10.1002/anie.202312874

Authors: Cataffo, Andrea; Pena-Lopez, Miguel; Pedrazzani, Riccardo; Echavarren, Antonio M

Affiliations

Barcelona Inst Sci & Technol, Inst Chem Res Catalonia ICIQ CERCA, Av Paisos Catalans 16, Tarragona 43007, Spain - Author
Univ Rovira i Virgili, Dept Quim Analit & Quim Organ, C-Marcelli Domingo S-N, Tarragona 43007, Spain - Author
Universitat Rovira i Virgili , Institut Català d’Investigació Química - Author

Abstract

Two different classes of stereoselective cyclizations have been developed using a chiral auxiliary approach with commercially available [JohnPhosAu(MeCN)SbF6] as catalyst. First, a stereoselective cascade cyclization of 1,5-enynes was achieved using the Oppolzer camphorsultam as chiral auxiliary. In this case, a one-pot cyclization-hydrolysis sequence was developed to directly afford enantioenriched spirocyclic ketones. Then, the stereoselective alkoxycyclization of 1,6-enynes was mediated by an Evans-type oxazolidinone. A reduction-hydrolysis sequence was selected to remove the auxiliary to give enantioenriched β-tetralones. DFT studies confirmed that the steric clash between the chiral auxiliary and alkene accounts for the experimentally observed diastereoselective cyclization through the Si face.

Keywords

alkenesalkynesc-ncatalyzed reactionchiral auxiliariescycloisomerizationsenantioselective constructionenynesgold catalysisrearrangementspirocyclic ketonesuniqueAlkoxycyclizationChiral auxiliariesEnynesGold catalysisIntermolecular 2+2 cycloadditionSpirocyclic ketones

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Angewandte Chemie (International Ed. Print) due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2023, it was in position 14/231, thus managing to position itself as a Q1 (Primer Cuartil), in the category Chemistry, Multidisciplinary. Notably, the journal is positioned above the 90th percentile.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.03. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 1.09 (source consulted: FECYT Feb 2024)
  • Field Citation Ratio (FCR) from Dimensions: 3.44 (source consulted: Dimensions Jun 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-06-14, the following number of citations:

  • WoS: 9
  • Scopus: 12
  • OpenCitations: 9

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-06-14:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 13.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 13 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 7.65.
  • The number of mentions on the social network X (formerly Twitter): 15 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
  • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: http://hdl.handle.net/20.500.11797/imarina9331756

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Cataffo, Andrea) and Last Author (ECHAVARREN PABLOS, ANTONIO).